Wolves recovered from losing top scorer Raul Jimenez to a sickening head injury to inflict Arsenal's third consecutive home league defeat with a 2-1 win at the Emirates on Sunday.
The rest of the Wolves team had combined for just five goals in their previous nine league games, but Pedro Neto and Daniel Podence struck to hand the visitors a first win away to Arsenal since 1979.
Former Chelsea and Celtic striker Chris Sutton has been a campaigner for concussion subs and more investigation into the high percentage of former footballers suffering from neurodegenerative diseases.
"Jimenez clearly in a bad way. Has David Luiz been checked adequately?"
The lead was short-lived as Arsenal responded to score their first goal from open play in six league games.
Arsenal responded after the break to pin Nuno Espirito Santo's men back, but the home side again lacked inspiration and a clinical finish in the final third.
The Arsenal captain had his side's best chance for an equaliser but headed wide much to the dismay of Arteta on the sidelines.